Omega 3 Fish Oil and Inflammation

Some kind of inflammation is believed to lie behindOmega 6 and a direct source of EPA, for example,
most diseases of the 21st Century. For example,can only be found in oily fish and fish oil supplements.
heart disease, cancer, autoimmune diseases, psoriasis,Over the past 70 years or so our consumption of
Alzheimer's and many other conditions arefish has also dwindled to a fraction of what it used
characterised by increased levels of pro-inflammatoryto be, whereas our consumption of Omega 6 has
markers produced from Omega 6 essential fattyincreased.
acids found in meat, dairy products, vegetable oilsMany experts believe it is no coincidence that this
and processed foods.change in our diet has coincided with a rise in the
Although it is now well known that Omega 3 fattynumber of cases of heart disease, cancers and
acids from oily fish or fish oil supplements can offerinflammatory conditions. Fish oil certainly offers hope
significant health benefits, what is perhaps less wellnot only therapeutically, but also by reducing
known are the reasons why? Possibly the mostinflammation, we can reduce the risk of developing a
important health giving property of Omega 3 is itssignificant number of health problems in the first
apparent ability to reduce inflammation by inhibitingplace. Some research suggests that fish oil could
production of pro-inflammatory eicosanoids.even offer a safer alternative to non-steroidal
Eicosanoids - good and badanti-inflammatory drugs or NSAIDs.
No one yet fully understands the mechanismsFish oil versus NSAIDs
involved, but according to a number of experts,One recent study published in Surgical Neurology
including Artemis Simopoulos a world-renownedsuggested that Omega 3 fatty acids could possibly
authority on fish oil and director of the Centre forhelp treat neck and back pain. Joseph Maroon and
Genetics, Nutrition and Health, fish oil influences theJeffrey Bost from Pittsburgh University, investigated
type of eicosanoids that are produced by the body.over 200 people who had been treated for
Eicosanoids are hormone like messengers that arenon-surgical back and neck pain and all of who were
derived from essential fatty acids. To put it verytaking NSAIDs. The participants were given 2.4 gr of
simply, depending on the type of essential fatty acidOmega 3 for 2 weeks before halving the dose and
incorporated into the cells, either Omega 6 or Omegareducing their NSAIDs over the following couple of
3, the eicosanoids produced will either be (bad)weeks. The results of surveys that were sent out
pro-inflammatory or (good) anti-inflammatory. It is(125 questionnaires were returned) showed that
necessary to have a balance between the differentmore than 50% had stopped taking any NSAIDs and
types of eicosanoids or between Omega 6 andhad less pain and 88% said they would continue
Omega 3, for good health and this is where diettaking fish oil supplements.
plays a crucial part. Most of us simply do not getSo what kind of fish oil is best?
enough of Omega 3 in our diet to offset theOpinions on this vary but in general, fish oil with a
inflammation produced by Omega 6.high EPA content can be considered the best for
In particular, it is the Omega 3 fatty acidmost people. Most fish oils contain a combination of
Eicosapentaenoic acid or EPA that can be consideredEPA and DHA and many reports mention just Omega
as the most beneficial for ongoing physical health and3 and do not differentiate between the fatty acids
mental wellbeing. Although Docosahexaenoic acid orinvolved. Some studies have indicated that too much
DHA, another Omega 3 fatty acid, is important forDHA might actually inhibit the effectiveness of EPA
the structure of the brain and healthy vision, manyso the ratio of EPA to DHA is crucial.
professionals now believe it is EPA that is needed forConclusion
the body and the brain to function well on a day toAs most people have a diet that is rich in Omega 6
day basis.but deficient in Omega 3, nearly everyone can
For example, when the Omega 6 fatty acid,benefit from supplementing with Omega 3 fish oil in
arachidonic acid or AA is incorporated into the cells,order to reduce or limit the negative effect of too
the result is increased production of pro-inflammatorymuch inflammation in the body. Eating more oily fish is
eicosanoids (prostaglandins, thromboxanes andone way of increasing intake of Omega 3, but as our
leukotrienes). EPA, in a way, competes with AA forfish are now polluted with toxins, the best option has
incorporation into the cells, reducing the number ofgot to be a quality fish oil supplement where the
pro-inflammatory compounds produced.toxins have been removed and one that is particularly
Unfortunately, Omega 3 is not as abundant ashigh in EPA.