| Parkinson's is found all over the world. Exact global | | | | Carbon monoxide poisoning. |
| figures are not always available, though it is | | | | Hydrocephalus. |
| estimated that four million people worldwide have the | | | | Signs and Symptoms of Parkinsons Disease |
| condition. Parkinson's disease belongs to a group of | | | | Common Sign and Symptoms of Parkinsons Disease |
| conditions called movement disorders. Parkinson's | | | | Depression and other emotional changes. |
| disease afflicts 1 to 1 1/2 million people in the United | | | | Difficulty in swallowing. |
| States. The disorder occurs in all races but is | | | | Chewing, and speaking. |
| somewhat more prevalent among Caucasians. People | | | | Urinary problems. |
| with the disease may have trouble walking, talking or | | | | Constipation. |
| doing simple tasks. Dysfunctional antioxidative | | | | Skin problems. |
| mechanisms are associated with older age as well, | | | | Sleep disruptions. |
| suggesting that the acceleration of age-related | | | | Trembling of hands, arms, legs, jaw and face. |
| changes in dopamine production may be a factor. | | | | Treatment of Parkinsons Disease |
| Parkinson's disease patients have at least one relative | | | | Common Treatment of Parkinsons Disease |
| with parkinsonian symptoms, suggesting that a | | | | Successful treatment of Parkinson's disease involves |
| genetic factor may be involved. There is no cure for | | | | much more than just the use of drugs. Levodopa and |
| Parkinson's at present, drugs are used to try to | | | | carbidopa combined (Sinemet) is the mainstay of |
| control symptoms of Parkinson's. The most widely | | | | Parkinson's therapy. |
| used form of treatment is L-dopa in various forms. | | | | Tolcapone inhibits the COMT enzyme, thereby |
| L-dopa is transformed into dopamine in the | | | | prolonging the effects of L-dopa, and so has been |
| dopaminergic neurons by L-aromatic amino acid | | | | used to complement L-dopa. |
| decarboxylase (often known by its former name | | | | The most widely practiced treatment for the speech |
| dopa-decarboxylase). The most widely practiced | | | | disorders associated with Parkinson's disease is Lee |
| treatment for the speech disorders associated with | | | | Silverman Voice Treatment (LSVT). |
| Parkinson's disease is Lee Silverman Voice Treatment | | | | Nutrients have been used in clinical studies and are |
| (LSVT). LSVT focuses on increasing vocal loudness. | | | | widely used by people with Parkinson's disease in |
| Regular physical exercise and/or therapy can be | | | | order to partially treat PD or slow down its |
| beneficial to the patient for maintaining and improving | | | | deterioration. |
| mobility, flexibility, balance and a range of motion. | | | | Catechol O-methyl transferase (COMT) inhibitors act |
| Nutrients have been used in clinical studies and are | | | | by inhibiting catabolism of dopamine, thereby |
| widely used by people with Parkinson's disease in | | | | extending L-dopa's peripheral half-life. |
| order to partially treat PD or slow down its | | | | Surgical treatment for PD is generally considered for |
| deterioration. | | | | patients who respond to medications. |
| Causes of Parkinsons Disease | | | | Azilect was approved for use as an initial single drug |
| Common Causes and Risk factors of Parkinsons | | | | therapy in early Parkinson's disease. Azilect |
| Disease | | | | (rasagiline), a new molecular entity, for the treatment |
| Free radicals. | | | | of Parkinson's disease. |
| Accelerated aging. | | | | Physical therapy can help strengthen and tone |
| Environmental toxins. | | | | underused muscles, and give rigid muscles a better |
| Genetic factors. | | | | range of motion. |
| Trauma. | | | | |