| Age eventually conquers all. As our bodies age, we | | | | the market today, but it should be remembered that |
| undergo a significant transformation in cell structure, | | | | they are not all created equal. Three things are very |
| hormones, bone and muscle mass, and cognitive | | | | important to consider when choosing a |
| abilities. This recipe is added to by the potential for | | | | Resveratrol-containing supplement. |
| heart disease, diabetes, neurological disorders such as | | | | Mixed-polyphenols. Resveratrol supplements should |
| Alzheimer's, and cancer. All in all, not a pretty picture. | | | | include a healthy dose of Quercetin and red wine |
| Yet, some people age better than others, and live a | | | | grape extracts (remember 17 polyphenols in red wine |
| long healthy life. Scientists have proven that diet, | | | | grapes were found to activate SIRT survival genes). |
| exercise, mental activity and nutritional supplements | | | | According to Dr. Joseph Maroon in an article published |
| can not only prolong life, but also can allow us to lead | | | | by Bottom Line Health, in September 2009 (The |
| healthier lives. To understand that people have | | | | Simple Supplement that May Prevent killer Diseases - |
| accepted these discoveries, one need only look at | | | | All about resveratrol), "because Resveratrol |
| the explosive growth in health foods, organic foods, | | | | absorption is thought to be enhanced when combined |
| and nutritional supplements. | | | | with other natural polyphenols, a mixed-polyphenol |
| Researchers have known since the 1930s that | | | | supplement is best." [Dr. Maroon is a professor of |
| organisms, animals, and even humans can live a | | | | neurological surgery at the University of Pittsburgh |
| longer, healthier lives through calorie restriction, which | | | | Medical Center (UPMC) and author of The Longevity |
| activates "survival genes" later discovered to be | | | | Factor: How Resveratrol and Red Wine Activate |
| sirtuin (SIRT) genes and enzymes. Most recently, | | | | Genes for a Longer and Healthier Life |
| discoveries by Dr. Joseph Baur and Dr. David Sinclair | | | | High Resveratrol Dosage. Scientific studies in both |
| at Harvard Medical School in 2006, coupled with many | | | | animals and humans have shown that a high |
| follow on studies, have shown that there are natural | | | | Resveratrol dosage is required to activate sirtuins. A |
| plant extracts that can activate sirtuins and mimic | | | | daily dosage of 300 - 500 mg is recommended from |
| calorie restriction, without having to dramatically | | | | data in both human studies, and animal studies (which |
| restrict calorie intake. | | | | calculate equivalent human dosages). Furthermore, |
| These natural plant extracts were discovered after | | | | studies reviewed by the FDA have shown no toxicity |
| investigating over 20,000 compounds. Nineteen (19) | | | | to humans even at dosages in the 5,000 mg range |
| of these compounds (all polyphenols with strong | | | | and beyond. |
| antioxidant properties) were identified, and 17 are | | | | Dr. James Smoliga studied humans in 2006, giving |
| found in red wine grapes, including Resveratrol and | | | | them a dosage of 400 mg of Resveratrol along with |
| Quercetin. Futhermore, it has been proven that the | | | | red wine grape extracts. His studies showed a |
| combination of these polyphenols allow them to | | | | marked improvement in strength, memory, and |
| remain in the blood stream, and in contact with cells | | | | endurance. |
| longer after being ingested. | | | | Resveratrol Quality. Not all Resveratrol is created |
| Studies on fish, mice, and worms and flies have | | | | equal. The best Resveratrol is from polygonum |
| shown that lifespan, and healthy lifespan, can be | | | | cuspidatim (Japanese Knotweed), and is at least 98% |
| prolonged by 60%, 25%, and 30% respectively using | | | | pure trans-Resveratrol. Many products use only 20% |
| Resveratrol and a normal calorie diet. | | | | or 50% purity ingredients. Supplements claims of |
| Resveratrol is "all the rage" these days, and is | | | | "pure resveratrol" are meaningless without the |
| growing in leaps and bounds in terms of its inclusion in | | | | percentage of purity. If the label doesn't list the |
| supplements, foods, etc. It should again be noted | | | | purity, you don't know what you're getting. Read the |
| that while Resveratrol has the highest SIRT gene | | | | supplement labels and website specifications of |
| activation, other polyphenols found in red wine | | | | products. |
| grapes, are not far behind, and work in concert with | | | | Furthermore, the nutraceutical supplement should be |
| Resveratrol. | | | | manufactured in a processing plant that has important |
| Latest Medical Research | | | | certifications including FDA, TGA, and GMP (Good |
| Extensive medical research has been conducted by | | | | Manufacturing Practices), which ensure the |
| university professors, pharmaceutical companies, and | | | | supplement contains to contaminants and undergoes |
| nutraceutical companies into the medical benefits of | | | | extensive testing. Again, check the websites. |
| red wine extracts, Quercetin, and Resveratrol. | | | | In addition to taking a high-quality nutraceutical |
| These studies have shown many health benefits | | | | supplement, it is highly recommended that people |
| including: anti-inflammation, blood thinning and reduced | | | | maintain a balanced diet, average weight, exercise, |
| risk for artery clotting (anti-coagulant), normalization | | | | avoid smoking, and eat foods rich in antioxidant |
| of blood sugar (for diabetes), increase mental | | | | polyphenols including red wine, grape juice, dark |
| capacity and memory, increase in strength and | | | | chocolate, green tea, and blueberries. |
| endurance, removal of amyloid-beta protein that | | | | Medical science has grown exponentially over the last |
| causes brain damage associated with Alzheimer's, and | | | | century. During that period, the average lifespan of |
| even the inhibition of many types of cancers (lung, | | | | humans has increased an average of 3 months each |
| colon, skin, liver and pancreatic). | | | | year, or 30 years total. Current advancements in |
| Can it really be that all of these age-related issues | | | | nutrition, such as the discovery of Resveratrol, |
| may be dealt with using simply plant polyphenols | | | | Quercetin, and red wine grape polyphenols may be a |
| compounds? Quite possibly, the answer is yes. | | | | key ingredient to continued advancements in |
| Red Wine and Resveratrol Supplements | | | | longevity research leading to longer, healthier lives. |
| There are hundreds of Resveratrol supplements on | | | | |