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Classification of Brain Tumor

Brain Tumor location in the brain. Undifferentiated
A brain tumor - primary or secondary - neuroectodermal tumors of the cerebellum
can cause a variety of signs and symptoms have historically been referred to as
because it can directly press on or medulloblastomas, while tumors of
invade brain tissue. This can damage or identical histology in the pineal region
destroy areas responsible for sight, would be diagnosed as pineoblastomas. The
movement, balance, speech, hearing, nomenclature of pediatric brain tumors is
memory or behavior. Brain tumor symptoms controversial and potentially confusing.
vary from patient to patient, and most of Some pathologists advocate abandoning the
these symptoms can also be found in traditional morphologically-based
people who do NOT have brain tumors. classifications such as medulloblastoma
Therefore, the only sure way to tell if in favor of a terminology that relies
you have a brain tumor or not is to see more extensively on the phenotypic
your doctor and get a brain scan. The characteristics of the tumor.
growth of abnormal cells in the tissues Primary Brain Tumor
of the brain. Brain tumors can be benign Astrocytomas - these tumors arise from
(non-cancerous) or malignantA primary small, star-shaped cells called
brain tumor is a group (mass) of abnormal astrocytes. They may grow anywhere in the
cells that start in the brain. This brain or spinal cord. In adults,
article focuses on primary brain tumors astrocytomas most often arise in the
in adults. Brain tumors encompass cerebrum. In children, they occur in the
neoplasms that originate in the brain brain stem, the cerebrum and the
itself (primary brain tumors) or involve cerebellum. A grade III astrocytoma is
the brain as a metastatic site. Brain sometimes called anaplastic astrocytoma.
tumors (metastatic brain tumors), which A grade IV astrocytoma is usually called
are malignant, are more common. These glioblastoma multiforme.
tumors result from cancer that started Brain stem gliomas - These tumors occur
elsewhere in the body and spread in the lowest, stem-like part of the
(metastasized) to the brain. brain. The brain stem controls many vital
Classification functions. Most brain stem gliomas are
HISTOPATHOLOGIC CLASSIFICATION - Primary high-grade astrocytomas.
brain tumors are classified by light Secondary Brain Tumor
microscopy according to their predominant Metastatic brain tumors originate from
cell type and graded based upon the malignant tumors located primarily in
presence or absence of standard other organs. Their incidence is higher
pathologic features. Historical attempts than that of primary brain tumors. The
at developing a classification system for most frequent types of metastatic brain
brain tumors date back to the 1830s. The tumors originate in the lung skin
German pathologist Rudolf Virchow first (malignant melanoma, kidney
introduced the term "glioma" in 1860. (hypernephroma, breast (breast
Virchow was also the first to attempt a carcinoma), and colon (colon carcinoma).
correlation of microscopic to macroscopic These tumor cells reach the brain via the
features of CNS tumors. blood-stream.
Cellular Classification-He classification Some non-tumoral masses and lesions can
of brain tumors is based on both mimic tumors of the central nervous
histopathological characteristics and system.




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