Bone Cancer: Causes, Symptoms, Diagnosis, Treatment and Prognosis

Bone cancer is rare and accounts for less than 1% ofDiagnosing bone cancer involves a number of tests,
all new tumors. Not all bone tumors are fatal in factincluding: X-rays and bone scans to show the exact
benign (non cancerous) abnormalities are morelocation and size of the cancer (these are always
common than malignant ones. Most bone cancers aredone prior to biopsy), bone biopsy where a small
secondary and have been spread from another site.sample of the cancer is removed from the bone and
Primary bone cancer which starts in the bone is quiteexamined in the laboratory for the presence of
rare constituting less than one per cent of allmalignant cells, Magnetic Resonance Imaging (MRI)
malignant tumors. They are more common in males,scan similar to a CT scan but uses magnetism instead
especially in children and adolescents. The mostof x-rays to build three-dimensional pictures of your
common type of primary bone cancer isbody.
osteosarcoma. This type of carcinoma usually affectsTreatment
young adults. It can affect any bone, but the arms,The treatment and prognosis of bone cancer depend
legs and pelvis are more commonly affected. Otherupon multiple factors including the type and extent of
less common forms of primary bone cancer includethe cancer, the patient's age and overall health status.
Ewing sarcoma, malignant fibrous histiocytoma andTumors may be treated with surgery, radiation
chondrosarcoma.therapy, chemotherapy, or a combination of these.
Primary Bone CancerPrimary bone cancers:
The causes of primary bone tumours are not known;The tumor, surrounding bone tissue and nearby
however, adults who have Pagets disease (a bonelymph nodes are surgically removed. In severe cases,
disease) may have an increased risk.the affected limb may need to be amputated, but
Secondary bone cancerthis is rare. Treatment may also include radiotherapy
Secondary bone cancer is the most common bone(x-rays to target and kill the cancer cells) and
cancer. It is a carcinoma that starts somewhere elsechemotherapy (anti-cancer drugs). These may be
in the body and spreads (metastasises) to the bone.given before surgery, to shrink the cancer and/or
The most common cancers that spread to the boneafterwards to destroy any remaining cancer cells.
originate in the breast, prostate, lung, kidney andSecondary bone cancer:
thyroid.Treatment depends on the treatment for the original
Reticulum cell sarcoma of the bonetumor, but usually includes chemotherapy,
A cancerous tumor of the bone marrow presenting inradiotherapy or hormone therapy. Surgery may be
more males than females.needed to strengthen the affected bone.
LeukaemiaPrognosis
Cancer of the blood, which starts in the boneOverall, the chance of recovery (prognosis) for bone
marrowcancers has improved significantly since the
Symptoms of bore cancerdevelopment of modern chemotherapy. The chance
Symptoms tend to develop slowly and depend onof recovery will depend on a variety of influences; if
the type, location, and size of the tumor. The signsthe cancer has spread, the type of bone cancer, the
and symptoms of bone cancer include: painful bonessize of the tumour, location, the person's general
and joints, swelling of bones and joints, problems withhealth and other individual factors.
movement, susceptibility to fractures. Less commonIf the tumor is very small and localized, the five-year
symptoms include: unexplained weight loss, tiredness,survival rate is close to 90 percent. If the cancer has
fever and sweating.begun to spread, however, survival becomes more
Remember bone cancer is very rare so if you havedifficult. The five-year survival rate is only about 60
any of these symptoms it is likely to be caused bypercent, and the prognosis is poor once the cancer
another condition. Always see your doctor if youspreads.
have for a diagnosis.Bone cancer in cats and dogs
CausesBone carcinoma in dogs and cats can be a challenging
Although bone cancer does not have a clearlydisorder. Osteosarcoma is by far the most common
defined cause, researchers have identified severalbone tumour if dogs, usually striking the leg bones of
factors that increase the likelihood of developinglarger breeds. Chemotherapy significantly prolongs the
these tumors. A small number of bone cancers aresurvival of animals with osteosarcoma when used in
due to heredity.conjunction with surgery. For dogs Cisplatin alone or
Diagnosisin combination with doxorubicin markedly improves
Bone cancer can present itself in any of the bones ofsurvival time to a median of 8-10 months with the
the body, but it is diagnosed most often in the longpercentage of dogs alive after11 months at 50%.
bones of the arms and legs.