Preventing brain diseases
 

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Article #325: What Is Parkinson Disease

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Parkinson disease is a brain disorder of genetic factors and environmental
that affects nearly 1.5 million Americans exposures." (National Parkinson
and 60,000 new cases are diagnosed Foundation)
annually. There is no known cure but with Parkinson's isn't easy to diagnose
research and medication there is hope. either. There is no blood test or brain
A British physician, Dr. James Parkinson, scan that definitively points to the
first described the disease in 1817. It condition - doctors diagnose based on the
is characterized by slowness, tremors, process of elimination and patient
stiffness and a loss of balance. Only two symptoms. Other signs of the disease
of these symptoms need to be present, include: a shuffling walk, small cramped
especially if they are more apparent on handwriting, muffled speech, depression
one side of the body over the other, for and stiff facial expressions. There are
a diagnosis of the condition to be made. doctors, neurologists, who specialize in
Brain cells called neurons are the treatment of neurological disorders
responsible for passing along electrical and of these even more specialized
impulses throughout the brain, from one practioners who specifically treat
cell to the next, allowing the brain to Parkinson disease.
function normally. In Parkinson disease, There are treatment options available to
cells in a certain part of the brain ease the symptoms of the disease. Most of
called the substantia nigra begin to die the hallmarks of Parkinson disease are
or become impaired. These cells are caused by the lack of dopamine-producing
particularly important because they cells existing or still functioning in
produce a chemical called dopamine. This the brain, so conventional treatment
chemical is responsible for smooth and includes medications that mimic or
coordinated movement of the body's replace dopamine. This helps to reduce
muscles. According to the National the stiffness, tremors, slow movement and
Parkinson Foundation, "When approximately poor balance associated with the
80% of the dopamine-producing cells are condition. Several promising new
damaged, the symptoms of Parkinson medicines are being developed and studied
disease appear." to halt the progression of the disease,
So who's at risk for developing Parkinson too.
disease? Almost everyone; the disease Surgery can be another option to help
doesn't seem to be selective and affects ease the symptoms for some Parkinson
women and men equally; and while it is sufferers - brain surgery can be
generally considered a disease of the dangerous so this is most often only
elderly that occurs after the age of 65, considered after treatment with
about 15% of the affected population are medication seems ineffective.
diagnosed under the age of 50. Parkinson There is currently no cure for Parkinson
affect 1 out of every 100 people and disease, but there is support and
there doesn't seem to be any social, treatment available; and with researchers
ethnic, economic or geographic boundaries working diligently to develop medications
either. "Currently, researchers suspect to halt the progression of the disease,
that the cause of Parkinson disease in there is also hope for the future.
most individuals reflects a combination






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